Clients
Perceptive Advisors serves 26 clients, 25 of them pooled investment vehicles. The average client has about $453 million with the firm.
- Pooled investment vehicles25 clients99%
- Other1 clients1%
Show client breakdownHide client breakdown
| Client type | Clients | Regulatory AUM | Share | Avg. per client |
|---|---|---|---|---|
| Pooled investment vehicles | 25 | $11,655,707,855 | 99.1% | $466.2M |
| Other | 1 | $109,607,775 | 0.9% | $109.6M |
| Total | 26 | $11,765,315,630 | 100% | $452.5M |
- Clients
- 25
- Regulatory AUM
- $11,655,707,855
- Share
- 99.1%
- Avg. per client
- $466.2M
- Clients
- 1
- Regulatory AUM
- $109,607,775
- Share
- 0.9%
- Avg. per client
- $109.6M
Total
- Clients
- 26
- Regulatory AUM
- $11,765,315,630
- Share
- 100%
- Avg. per client
- $452.5M
What it does
Perceptive Advisors provides portfolio management for pooled vehicles and other activities. It is paid through a percentage of assets and performance-based fees.
Perceptive Advisors advises 17 private funds.
100.0% of assets ($11.77B across 26 accounts) are managed with discretion. 28% of clients are outside the U.S., and 0 clients received advice without assets under management last fiscal year.
What the accounts hold
- Stocks82%
- Non-exchange-traded equities64%
- Exchange-traded equities18%
- Funds16%
- Bonds2%
Custodians
Perceptive Advisors’ client accounts are held mainly at Bofa Securities, with 0% of managed assets. Perceptive Advisors has custody of $11.77B for 26 clients.
- OtherBofa Securities, All other custodians100%
Ownership and leadership
Joseph Edelman owns 75% or more of Perceptive Advisors, and Joseph Edelman is its CEO.
- Owns 75% or more of Perceptive Advisors LLC.
Joseph Edelman
Control person · since December 2000
- Owns 10% to 25% of Perceptive Advisors LLC.
Adam Stone
Control person · since December 2025
Leadership
- Joseph EdelmanChief Executive Officer and Portfolio Manager
- Shmuel CohnChief Financial Officer
- James MannixChief Operating Officer
- Alexander RakitinChief Compliance Officer
- Marcel RosnerGeneral Counsel
- Adam StoneChief Investment Officer
Staff
- 49 employees
- 28 in advisory functions
Reported holdings
Perceptive Advisors’ reported 13F holdings total $6.66B across 109 positions, and the ten largest make up 47.3% of it.
- $6.66B
- Reported 13F value
- 109
- Positions
- 47.3%
- In the 10 largest
- +30.2%
- Value vs. prior quarter
- Praxis Precision Medicines I10.2%
- Spyre Therapeutics Inc.5.8%
- Celcuity Inc.5.0%
- Ascendis Pharma A/s4.7%
- Rhythm Pharmaceuticals Inc.4.3%
- Roivant Sciences Ltd4.3%
- Relay Therapeutics Inc.4.0%
- Travere Therapeutics Inc.3.2%
- Kardigan Inc.2.9%
- Nuvalent Inc.2.9%
Together, the ten largest are 47.3% of reported value.
A 13F covers only exchange-traded long positions the firm holds with discretion, so this $6.66B is not its $11.77B in regulatory assets and does not represent any individual client's portfolio.
Fees
Perceptive Advisors is paid through a percentage of assets under management and performance-based fees.
Perceptive Advisors’ fee rates are not included in this profile. Find its brochure on the SEC’s site.
Offices and registrations
Besides its headquarters, Perceptive Advisors has 4 offices, with 5 listed addresses across 4 states.
New York · 2 listed addresses
- 51 Astor Place, 10th FLR, New YorkHQ
- 56 Flying Point Road, Water Mill
Connecticut · 1 listed address
- 2 Greenwich Office Park, Greenwich
Florida · 1 listed address
- 929 Alton RD., Miami Beach
Wyoming · 1 listed address
- 145 North Connor Street, Sheridan
Registration details
- Legal name
- Perceptive Advisors LLC.
- Headquarters
- 51 Astor Place, 10th FLR, New York, NY 10003
- Phone
- 646-205-5300
- Website
- Not reported
- SEC file
- 801-71841
- Structure
- Delaware LLC
- Fiscal year end
- December
This directory does not report disciplinary history, for any firm or individual, in either direction. The SEC publishes the complete record, including any disciplinary events, and it is the authoritative place to check one. See this firm's record on adviserinfo.sec.gov
Common questions
How many clients does Perceptive Advisors have?
Perceptive Advisors has 26 clients and manages $11.8 billion for them, as of July 2026. They include 25 pooled investment vehicles and 1 other clients.
Source: Form ADV Part 1A, Items 5.D and 5.F, filed 13 July 2026
What services does Perceptive Advisors offer?
Perceptive Advisors provides portfolio management for pooled vehicles and other activities.
Source: Form ADV Part 1A, Item 5.G, from the SEC's 2 October 2026 data file
Which custodians does Perceptive Advisors use?
Perceptive Advisors’ separately managed account assets are held at Bofa Securities, Inc. (New York, NY), with $15,435,443. Only custodians holding at least a tenth of those assets are named.
Source: Form ADV Part 1A, Schedule D, Section 5.K.(3), filed 13 July 2026
How many financial advisors does Perceptive Advisors have?
Perceptive Advisors has 0 investment adviser representatives registered with state securities authorities, out of 49 employees, and 28 perform investment advisory functions. None are registered representatives of a broker-dealer or licensed insurance agents.
Source: Form ADV Part 1A, Items 5.A and 5.B, from the SEC's 2 October 2026 data file
What does Perceptive Advisors invest in?
At the end of its last fiscal year, Perceptive Advisors’ separately managed accounts held 64% non-exchange-traded equities, 18% exchange-traded equities, 16% pooled vehicles (private funds and similar) and 2% high-yield corporate bonds. It advises 17 private funds.
Source: Form ADV Part 1A, Items 5.K.(1) and 7.B, from the SEC's 2 October 2026 data file
Who owns Perceptive Advisors?
Perceptive Advisors’ direct owners are Joseph Edelman (75% or more) and Adam Stone (10% to 25%).
Source: Form ADV Part 1A, Schedules A and B, filed 13 July 2026
How does Perceptive Advisors get paid?
Perceptive Advisors is paid through a percentage of assets under management and performance-based fees. Its Form ADV lists no commissions among how it is paid.
Source: Form ADV Part 1A, Item 5.E, from the SEC's 2 October 2026 data file