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Avoro Capital Advisors reported holdings

Quarter ended 30 June 2026. Filed with the SEC on 14 August 2026, signed by Scott Epstein, Chief Compliance Officer & COO. Retrieved 14 October 2026.

$11.14B
Reported 13F value
26
Positions
79.5%
In the 10 largest
+9.6%
Value vs. prior quarter

Avoro Capital Advisors’ reported 13F holdings total $11.14B across 26 positions as of 30 June 2026. The ten largest make up 79.5% of it, and its value rose 9.6% from the prior quarter.

Form 13F lists long positions in exchange-traded securities over which the filer had investment discretion, valued at quarter end. It excludes cash, bonds held outside 13(f) securities, private funds, and assets the firm does not have discretion over, so the $11.14B reported here is not the firm's $13.55B in regulatory assets, and it does not represent any individual client's portfolio.

Largest positions

United Therapeutics Corp.Common$1,505,082,912
Class
Common
Share
13.5%
Ascendis PharmaORDINARY SHARES$1,363,235,526
Class
ORDINARY SHARES
Share
12.2%
Krystal Biotech Inc.Common$1,073,713,003
Class
Common
Share
9.6%
Madrigal Pharmaceuticals Inc.Common$984,408,154
Class
Common
Share
8.8%
Argenx SESponsored ADR$927,770,000
Class
Sponsored ADR
Share
8.3%
Arrowhead Pharmaceuticals Inc.Common$925,591,288
Class
Common
Share
8.3%
Kymera Therapeutics Inc.Common$857,129,238
Class
Common
Share
7.7%
Revolution Medicines Inc.Common$430,182,160
Class
Common
Share
3.9%
Cytokinetics Inc.Common$425,949,915
Class
Common
Share
3.8%
Celcuity Inc.Common$355,708,000
Class
Common
Share
3.2%
Structure Therapeutics Inc.SPONSORED ADS$351,836,637
Class
SPONSORED ADS
Share
3.2%
Xenon Pharmaceuticals Inc.Common$348,746,620
Class
Common
Share
3.1%
Definium Therapeutics Inc.Common$338,165,292
Class
Common
Share
3.0%
Uniqure NVCommon$309,881,409
Class
Common
Share
2.8%
Vera Therapeutics Inc.Common$245,612,034
Class
Common
Share
2.2%
Taysha Gene Therapies Inc.Common$162,683,327
Class
Common
Share
1.5%
Ocular Therapeutix Inc.Common$123,142,800
Class
Common
Share
1.1%
Damora Therapeutics Inc.Common$98,395,830
Class
Common
Share
0.9%
Hemab Therapeutics Hldgs Inc.Common$70,710,760
Class
Common
Share
0.6%
GH Research PLCORDINARY SHARES$48,384,000
Class
ORDINARY SHARES
Share
0.4%
Viridian Therapeutics Inc.Common$45,925,000
Class
Common
Share
0.4%
Septerna Inc.Common$44,792,875
Class
Common
Share
0.4%
Avalo TherapeuticsCommon$43,119,994
Class
Common
Share
0.4%
Faeth Therapeutics Inc.COMMON$36,100,975
Class
COMMON
Share
0.3%
Whitehawk Therapeutics Inc.Common$13,050,261
Class
Common
Share
0.1%
Lexeo Therapeutics Inc.Common$6,932,175
Class
Common
Share
0.1%

The share class is shown on a wider screen.

The 26 largest of 26 positions by value, with holdings of the same security combined. Share counts and quarter-on-quarter changes for each position are on EDGAR. View the full information table on EDGAR

This filing

Form
13F-HR
CIK
1633313
File number
028-16573
Options
0 call, 0 put
In the 25 largest
99.9%
Prior quarter
$10,164,789,055 at 31 March 2026
Positions opened
3
Positions closed
9

Common questions

What are Avoro Capital Advisors’ 13F holdings worth?

$11,136,250,185 across 26 positions for the quarter ended 30 June 2026.

What is Avoro Capital Advisors’ largest 13F holding?

UNITED THERAPEUTICS CORP (Common) was the largest position at $1,505,082,912, or 13.5% of reported 13F value, as of 30 June 2026.

How concentrated is Avoro Capital Advisors’ 13F portfolio?

The ten largest positions accounted for 79.5% of reported value and the twenty-five largest for 99.9%, across 26 positions as of 30 June 2026.

Does Form 13F show everything Avoro Capital Advisors manages?

No. Form 13F covers only long positions in exchange-traded securities over which the manager has investment discretion, valued at quarter end. It excludes cash, most bonds, private funds, and any assets the firm does not have discretion over, so it is neither the firm's total assets nor any individual client's portfolio.

How often does Avoro Capital Advisors file its 13F?

Every quarter. Managers file within 45 days of each quarter's end, so the figures are a snapshot that changes between filings. This page shows the quarter ended 30 June 2026.

Answered from this filing and the prior quarter's.

Back to the Avoro Capital Advisors profile

Sources

  1. Form 13F-HR, accession 0001104659-26-096427, filed 14 August 2026 for the quarter ended 30 June 2026.
  2. Form 13F-HR, accession 0001104659-26-061754, filed 15 May 2026 for the quarter ended 31 March 2026.
  3. All 13F filings by this firm on EDGAR.

Retrieved 14 October 2026. Values are as reported by the filer in whole dollars; percentages and quarter-over-quarter figures are arithmetic on the filed tables.

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This page restates a public SEC filing for informational purposes only. It is not a recommendation of any security or of Avoro Capital Advisors LLC, and Niva Wealth is not affiliated with the firm. Holdings change; the filing reflects one quarter-end date.