Largest positions
| Issuer | Class | Value | Share |
|---|---|---|---|
| SPDR Series Trust (call option)STATE STREET SPD | STATE STREET SPD | $51.1M | 20.5% |
| SPDR Series Trust (put option)STATE STREET SPD | STATE STREET SPD | $51.1M | 20.5% |
| Verastem Inc.COM NEW | COM NEW | $17.5M | 7.0% |
| Tenax Therapeutics Inc.COM NEW | COM NEW | $15.6M | 6.2% |
| Adma Biologics Inc. (call option)COM | COM | $10.4M | 4.1% |
| Evolus Inc.COM | COM | $7.23M | 2.9% |
| Adma Biologics Inc.COM | COM | $6.67M | 2.7% |
| Camp4 Therapeutics Corp.COM | COM | $6.13M | 2.5% |
| Nektar TherapeuticsCOM NEW | COM NEW | $6.12M | 2.4% |
| Terns Pharmaceuticals Inc. (call option)COM | COM | $5.27M | 2.1% |
| Zevra Therapeutics Inc.COM NEW | COM NEW | $4.47M | 1.8% |
| Corbus Pharmaceuticals HldgsCOM NEW | COM NEW | $3.6M | 1.4% |
| Abeona Therapeutics Inc.COM NEW | COM NEW | $3.34M | 1.3% |
| Establishment Labs Hldgs Inc. (call option)COM | COM | $2.84M | 1.1% |
| Kazia Therapeutics LtdSPONSORED ADS | SPONSORED ADS | $2.57M | 1.0% |
| An2 Therapeutics Inc.COM | COM | $2.44M | 1.0% |
| Alexandria Real Estate EQ IN (call option)COM | COM | $2.32M | 0.9% |
| Acadia Pharmaceuticals Inc. (call option)COM | COM | $2.23M | 0.9% |
| Sol-gel Technologies LtdSHS NEW | SHS NEW | $2.2M | 0.9% |
| Xoma Royalty CorporationCOM NEW | COM NEW | $2.18M | 0.9% |
| Aytu Biopharma Inc.COM | COM | $2.16M | 0.9% |
| Curis Inc.COM | COM | $2.04M | 0.8% |
| Evolus Inc. (call option)COM | COM | $1.73M | 0.7% |
| Xeris Biopharma Holdings Inc. (call option)COM | COM | $1.62M | 0.7% |
| Tela Bio Inc.COM | COM | $1.62M | 0.6% |
| Inhibikase Therapeutics Inc.COM NEW | COM NEW | $1.61M | 0.6% |
| Crescent Biopharma Inc..COM | COM | $1.56M | 0.6% |
| Adicet Bio Inc.COM NEW | COM NEW | $1.51M | 0.6% |
| X4 Pharmaceuticals Inc.COM NEW | COM NEW | $1.38M | 0.6% |
| Okyo Pharma LtdSHS NEW | SHS NEW | $1.37M | 0.5% |
| SI Bone Inc. (call option)COM | COM | $1.26M | 0.5% |
| Mannkind Corp. (call option)COM NEW | COM NEW | $1.23M | 0.5% |
| Heron Therapeutics Inc.COM | COM | $1.12M | 0.4% |
| Pulmonx Corp.COM | COM | $991K | 0.4% |
| In8bio Inc.COM NEW | COM NEW | $982K | 0.4% |
| Neumora Therapeutics Inc.. (call option)COM | COM | $975K | 0.4% |
| Surrozen Inc.COM NEW | COM NEW | $961K | 0.4% |
| Cytomx Therapeutics Inc..COM | COM | $940K | 0.4% |
| Cytomx Therapeutics Inc.. (call option)COM | COM | $940K | 0.4% |
| Delcath Sys Inc. (call option)COM NEW | COM NEW | $928K | 0.4% |
| Ardelyx Inc. (call option)COM | COM | $899K | 0.4% |
| Pmv Pharmaceuticals Inc.COM | COM | $878K | 0.4% |
| Bioage Labs Inc.COM | COM | $875K | 0.4% |
| Connect Biopharma Hldgs LtdSHS | SHS | $812K | 0.3% |
| Heron Therapeutics Inc. (call option)COM | COM | $800K | 0.3% |
| Radiopharm Theranostics LtdSPONSORED ADS | SPONSORED ADS | $739K | 0.3% |
| Maxcyte Inc.COM | COM | $706K | 0.3% |
| Codexis Inc.COM | COM | $681K | 0.3% |
| Boundless Bio Inc.COM | COM | $657K | 0.3% |
| Cybin Inc.COM NEW | COM NEW | $643K | 0.3% |
SPDR Series Trust (call option)STATE STREET SPD$51.1M
- Class
- STATE STREET SPD
- Share
- 20.5%
SPDR Series Trust (put option)STATE STREET SPD$51.1M
- Class
- STATE STREET SPD
- Share
- 20.5%
Verastem Inc.COM NEW$17.5M
- Class
- COM NEW
- Share
- 7.0%
Tenax Therapeutics Inc.COM NEW$15.6M
- Class
- COM NEW
- Share
- 6.2%
Adma Biologics Inc. (call option)COM$10.4M
- Class
- COM
- Share
- 4.1%
Evolus Inc.COM$7.23M
- Class
- COM
- Share
- 2.9%
Adma Biologics Inc.COM$6.67M
- Class
- COM
- Share
- 2.7%
Camp4 Therapeutics Corp.COM$6.13M
- Class
- COM
- Share
- 2.5%
Nektar TherapeuticsCOM NEW$6.12M
- Class
- COM NEW
- Share
- 2.4%
Terns Pharmaceuticals Inc. (call option)COM$5.27M
- Class
- COM
- Share
- 2.1%
Zevra Therapeutics Inc.COM NEW$4.47M
- Class
- COM NEW
- Share
- 1.8%
Corbus Pharmaceuticals HldgsCOM NEW$3.6M
- Class
- COM NEW
- Share
- 1.4%
Abeona Therapeutics Inc.COM NEW$3.34M
- Class
- COM NEW
- Share
- 1.3%
Establishment Labs Hldgs Inc. (call option)COM$2.84M
- Class
- COM
- Share
- 1.1%
Kazia Therapeutics LtdSPONSORED ADS$2.57M
- Class
- SPONSORED ADS
- Share
- 1.0%
An2 Therapeutics Inc.COM$2.44M
- Class
- COM
- Share
- 1.0%
Alexandria Real Estate EQ IN (call option)COM$2.32M
- Class
- COM
- Share
- 0.9%
Acadia Pharmaceuticals Inc. (call option)COM$2.23M
- Class
- COM
- Share
- 0.9%
Sol-gel Technologies LtdSHS NEW$2.2M
- Class
- SHS NEW
- Share
- 0.9%
Xoma Royalty CorporationCOM NEW$2.18M
- Class
- COM NEW
- Share
- 0.9%
Aytu Biopharma Inc.COM$2.16M
- Class
- COM
- Share
- 0.9%
Curis Inc.COM$2.04M
- Class
- COM
- Share
- 0.8%
Evolus Inc. (call option)COM$1.73M
- Class
- COM
- Share
- 0.7%
Xeris Biopharma Holdings Inc. (call option)COM$1.62M
- Class
- COM
- Share
- 0.7%
Tela Bio Inc.COM$1.62M
- Class
- COM
- Share
- 0.6%
Inhibikase Therapeutics Inc.COM NEW$1.61M
- Class
- COM NEW
- Share
- 0.6%
Crescent Biopharma Inc..COM$1.56M
- Class
- COM
- Share
- 0.6%
Adicet Bio Inc.COM NEW$1.51M
- Class
- COM NEW
- Share
- 0.6%
X4 Pharmaceuticals Inc.COM NEW$1.38M
- Class
- COM NEW
- Share
- 0.6%
Okyo Pharma LtdSHS NEW$1.37M
- Class
- SHS NEW
- Share
- 0.5%
SI Bone Inc. (call option)COM$1.26M
- Class
- COM
- Share
- 0.5%
Mannkind Corp. (call option)COM NEW$1.23M
- Class
- COM NEW
- Share
- 0.5%
Heron Therapeutics Inc.COM$1.12M
- Class
- COM
- Share
- 0.4%
Pulmonx Corp.COM$991K
- Class
- COM
- Share
- 0.4%
In8bio Inc.COM NEW$982K
- Class
- COM NEW
- Share
- 0.4%
Neumora Therapeutics Inc.. (call option)COM$975K
- Class
- COM
- Share
- 0.4%
Surrozen Inc.COM NEW$961K
- Class
- COM NEW
- Share
- 0.4%
Cytomx Therapeutics Inc..COM$940K
- Class
- COM
- Share
- 0.4%
Cytomx Therapeutics Inc.. (call option)COM$940K
- Class
- COM
- Share
- 0.4%
Delcath Sys Inc. (call option)COM NEW$928K
- Class
- COM NEW
- Share
- 0.4%
Ardelyx Inc. (call option)COM$899K
- Class
- COM
- Share
- 0.4%
Pmv Pharmaceuticals Inc.COM$878K
- Class
- COM
- Share
- 0.4%
Bioage Labs Inc.COM$875K
- Class
- COM
- Share
- 0.4%
Connect Biopharma Hldgs LtdSHS$812K
- Class
- SHS
- Share
- 0.3%
Heron Therapeutics Inc. (call option)COM$800K
- Class
- COM
- Share
- 0.3%
Radiopharm Theranostics LtdSPONSORED ADS$739K
- Class
- SPONSORED ADS
- Share
- 0.3%
Maxcyte Inc.COM$706K
- Class
- COM
- Share
- 0.3%
Codexis Inc.COM$681K
- Class
- COM
- Share
- 0.3%
Boundless Bio Inc.COM$657K
- Class
- COM
- Share
- 0.3%
Cybin Inc.COM NEW$643K
- Class
- COM NEW
- Share
- 0.3%
The share class is shown on a wider screen.
The 50 largest of 83 positions by value, with holdings of the same security combined. The 83 largest are in this firm's machine-readable record. Share counts and quarter-on-quarter changes for each position are on EDGAR. View the full information table on EDGAR
This filing
- Form
- 13F-HR
- CIK
- 1440771
- File number
- 028-17175
- Options
- 16 call, 1 put
- In the 25 largest
- 85.9%
Common questions
What are Stonepine Capital Management’s 13F holdings worth?
$250 million across 83 positions for the quarter ended 31 March 2026.
What is Stonepine Capital Management’s largest 13F holding?
SPDR SERIES TRUST (STATE STREET SPD) was the largest position at $51.1 million, or 20.5% of reported 13F value, as of 31 March 2026.
How concentrated is Stonepine Capital Management’s 13F portfolio?
The ten largest positions accounted for 70.9% of reported value and the twenty-five largest for 85.9%, across 83 positions as of 31 March 2026.
Does Form 13F show everything Stonepine Capital Management manages?
No. Form 13F covers only long positions in exchange-traded securities over which the manager has investment discretion, valued at quarter end. It excludes cash, most bonds, private funds, and any assets the firm does not have discretion over, so it is neither the firm's total assets nor any individual client's portfolio.
How often does Stonepine Capital Management file its 13F?
Every quarter. Managers file within 45 days of each quarter's end, so the figures are a snapshot that changes between filings. This page shows the quarter ended 31 March 2026.
Answered from this filing and the prior quarter's.