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SR One Capital Management

Private funds

Redwood City, CACRD 306361Updated

SR One Capital Management is an investment adviser based in Redwood City, CA, registered with the SEC since 2020. It provides investment management. Its clients include pooled investment vehicles. Its regulatory assets under management total $2.44 billion, as filed on 31 March 2026.

19
Clients
Not reported
AUM per individual client
15
Advisory staff
2
Offices

From Form ADV filed 31 March 2026SEC record

Services and clients

SR One Capital Management provides portfolio management for pooled vehicles. The firm advises 19 private funds.

SR One Capital Management reports 19 pooled investment vehicles. These counts refer to investment vehicles, rather than the individual investors in them. Of its assets, 100.0% ($2.44B across 19 accounts) are managed with discretion.

Clients and assets by client type
Clients19 clients
Assets$2.44B
Client typeClientsAssets
Pooled investment vehicles100%100%
Client breakdown and activity details
Pooled investment vehicles
Clients
19
Regulatory AUM
$2.44B
AUM share
100.0%
Avg. per client
$128M

Total

Clients
19
Regulatory AUM
$2.44B
AUM share
100%
Avg. per client
$128M
Clients outside the U.S.
0%
Clients advised without assets under management last fiscal year
0
Private funds advised
19

Fees and minimums

SR One Capital Management is paid through a percentage of assets under management and performance-based fees; its fees and minimums are set out in its brochures on the SEC website.

Ownership and people

Simeon George owns 25% to 50% of SR One Capital Management. It has 28 employees, 15 of them in advisory roles.

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Staff

  • 28 employees
  • 15 in advisory functions
Who owns the firm
SR One Capital Management, LP· the adviser
  • Simeon George

    Control person · since October 2019

    Owns 25% to 50% of SR One Capital Management, LP
  • Rajeev Dadoo

    Control person · since October 2019

    Owns 25% to 50% of SR One Capital Management, LP

Growth and acquisitions

SR One Capital Management’s regulatory assets grew 3.5× from $691M (July 2021) to $2.44B (March 2026); clients rose from 1 to 19 and employees from 13 to 28.

By annual filing
Measure
Figures from each annual filing
FiledRegulatory AUMClientsStaffEmployeesOffices
Mar 2026March 2026$2.44B19282
Mar 2025March 2025$2.09B17303
Jul 2024July 2024$1.59B17243
Jun 2023June 2023$1.43B15243
Jun 2022June 2022$1.08B14213
Jul 2021July 2021$691M1132

Offices and registration details

Besides its headquarters, SR One Capital Management has 1 office, with 2 listed addresses in the U.S. and abroad.

Listed office addresses by state

California · 1 listed address

  • 929 Main Street, Suite 200, Redwood CityHQ

International offices

  • 6TH FLOOR, LONDON, W1G 0QF, United Kingdom

Contact and registration details

Legal name
SR One Capital Management, LP
Headquarters
929 Main Street, Suite 200, Redwood City, CA 94063
Website
srone.com
SEC file
801-119142
Structure
Delaware limited partnership
Fiscal year end
December

Custodians

SR One Capital Management has custody of $2.44B for 19 clients.

Investments and reported holdings

SR One Capital Management’s reported 13F holdings for the quarter ended 30 June 2026 total $1.04B across 15 positions; the largest are Veradermics, Inc.. (28.4%), Zenas Biopharma, Inc. (12.3%) and Crispr Therapeutics AG (10.7%).

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Common questions

How many clients does SR One Capital Management have?

SR One Capital Management has 19 clients and manages $2.44 billion for them, as of March 2026. They include 19 pooled investment vehicles.

Source: Form ADV Part 1A, Items 5.D and 5.F, filed 31 March 2026

What services does SR One Capital Management offer?

SR One Capital Management provides portfolio management for pooled vehicles.

Source: Form ADV Part 1A, Item 5.G, from the SEC's 2 October 2026 data file

How many financial advisors does SR One Capital Management have?

SR One Capital Management has 0 investment adviser representatives registered with state securities authorities, out of 28 employees, and 15 perform investment advisory functions. None are registered representatives of a broker-dealer or licensed insurance agents.

Source: Form ADV Part 1A, Items 5.A and 5.B, from the SEC's 2 October 2026 data file

Who owns SR One Capital Management?

SR One Capital Management’s direct owners are Simeon George and Rajeev Dadoo, each holding 50% or less.

Source: Form ADV Part 1A, Schedules A and B, filed 31 March 2026

How does SR One Capital Management get paid?

SR One Capital Management is paid through a percentage of assets under management and performance-based fees. Its Form ADV lists no commissions among how it is paid.

Source: Form ADV Part 1A, Item 5.E, from the SEC's 2 October 2026 data file

How do I contact SR One Capital Management?

SR One Capital Management’s main office is at 929 Main Street, Suite 200, Redwood City, CA 94063. Its phone number is 408-303-2673. Its website is srone.com.

Source: Form ADV Part 1A, Item 1.F, filed 31 March 2026

Sources and methodology

  1. Form ADV Part 1A, amendment filed 31 March 2026. Items 1, 5, 9, 11 and Schedules A, B and D.
  2. IAPD firm record, CRD 306361.
  3. SEC registered adviser data, annual Form ADV amendments filed 15 July 2021 to 31 March 2026. Items 1.F and 5.
  4. Form 13F-HR, filed 12 August 2026 for the quarter ended 30 June 2026.

Retrieved 15 October 2026. All are published by the SEC and may have been amended since. Disciplinary history is not yet shown here. The SEC publishes the complete record, including any disciplinary events, and it is the authoritative place to check one. The logo is reproduced for identification from SR ONE Capital Management, LP, website.

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