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Sio Capital Management reported holdings

Quarter ended 30 June 2026. Filed with the SEC on 14 August 2026, signed by Jin W. Lee, Chief Compliance Officer. Retrieved 14 October 2026. Page updated 21 October 2026.

Sio Capital Management’s reported 13F holdings total $604M across 59 positions as of 30 June 2026. The ten largest make up 48.6% of it, and its value fell 13.3% from the prior quarter.

$604M
Reported 13F value
59
Positions
48.6%
In the 10 largest
−13.3%
Value vs. prior quarter

Largest positions

Anteris Technologies GlobalCOM$54.6M
Class
COM
Share
9.0%
Cencora Inc.COM$49.1M
Class
COM
Share
8.1%
Maximus Inc.COM$38.5M
Class
COM
Share
6.4%
Allogene Therapeutics Inc.COM$27.7M
Class
COM
Share
4.6%
Globus Med Inc.CL A$23.8M
Class
CL A
Share
3.9%
Gsk PLCSPONSORED ADR$22.9M
Class
SPONSORED ADR
Share
3.8%
Tyra Biosciences Inc.COM$22.2M
Class
COM
Share
3.7%
Waystar Hldg Corp.COM$19M
Class
COM
Share
3.1%
Sellas Life Sciences Group I (put option)COM NEW$18.2M
Class
COM NEW
Share
3.0%
Ideaya Biosciences Inc.COM$17.9M
Class
COM
Share
3.0%
Oruka Therapeutics Inc.COM$16.9M
Class
COM
Share
2.8%
The Cigna GroupCOM$15.9M
Class
COM
Share
2.6%
Sanofi SASPONSORED ADR$15.5M
Class
SPONSORED ADR
Share
2.6%
Icon Pub Ltd COSHS$15.3M
Class
SHS
Share
2.5%
Viatris Inc.COM$15.2M
Class
COM
Share
2.5%
Cross Ctry Healthcare Inc.COM$14.5M
Class
COM
Share
2.4%
Rapport Therapeutics Inc.COM$12.8M
Class
COM
Share
2.1%
Abbott LaboratoriesCOM$11.7M
Class
COM
Share
1.9%
Celcuity Inc.COM$11.5M
Class
COM
Share
1.9%
Zimmer Biomet Holdings Inc.COM$11.3M
Class
COM
Share
1.9%
Regeneron PharmaceuticalsCOM$11.2M
Class
COM
Share
1.9%
Bristol-myers Squibb COCOM$11.1M
Class
COM
Share
1.8%
Medtronic PLCSHS$11.1M
Class
SHS
Share
1.8%
Vir Biotechnology Inc.COM$11M
Class
COM
Share
1.8%
Senseonics Hldgs Inc.COM$9.05M
Class
COM
Share
1.5%
Eyepoint Inc.COM NEW$8.91M
Class
COM NEW
Share
1.5%
Cybin Inc.COM NEW$8.59M
Class
COM NEW
Share
1.4%
Ani Pharmaceuticals Inc.COM$8.05M
Class
COM
Share
1.3%
Protara Therapeutics Inc.COM STK$7.34M
Class
COM STK
Share
1.2%
Relmada Therapeutics Inc.COM$6.94M
Class
COM
Share
1.1%
Tango Therapeutics Inc.COM$6.52M
Class
COM
Share
1.1%
Aquestive Therapeutics Inc.COM$6.18M
Class
COM
Share
1.0%
Dianthus Therapeutics Inc.COM$5.78M
Class
COM
Share
1.0%
Sionna Therapeutics Inc.COM$5.62M
Class
COM
Share
0.9%
Ocular Therapeutix Inc.COM$5.3M
Class
COM
Share
0.9%
Zenas Biopharma Inc.COM$5.29M
Class
COM
Share
0.9%
Bright Minds Biosciences Inc.COM NEW$5.19M
Class
COM NEW
Share
0.9%
Onkure Therapeutics Inc.COM CL A$4.92M
Class
COM CL A
Share
0.8%
Savara Inc.COM$3.8M
Class
COM
Share
0.6%
Pmv Pharmaceuticals Inc.COM$3.53M
Class
COM
Share
0.6%
Aveanna Healthcare Hldgs Inc.COM$3.16M
Class
COM
Share
0.5%
Ovid Therapeutics Inc.COM$2.7M
Class
COM
Share
0.4%
Immunome Inc.COM$2.63M
Class
COM
Share
0.4%
Hims & Hers Health Inc. (call option)COM CL A$2.6M
Class
COM CL A
Share
0.4%
An2 Therapeutics Inc.COM$2.56M
Class
COM
Share
0.4%
Serina Therapeutics Inc.COM SHS$1.94M
Class
COM SHS
Share
0.3%
Aligos Therapeutics Inc.COM NEW$1.89M
Class
COM NEW
Share
0.3%
Ibio Inc.COM NEW$1.58M
Class
COM NEW
Share
0.3%
Xilio Therapeutics Inc.COM$1.46M
Class
COM
Share
0.2%
Artivion Inc.COM$1.09M
Class
COM
Share
0.2%

The share class is shown on a wider screen.

The 50 largest of 59 positions by value, with holdings of the same security combined. The 59 largest are in this firm's machine-readable record. Share counts and quarter-on-quarter changes for each position are on EDGAR. View the full information table on EDGAR

This filing

Form
13F-HR
CIK
1482416
File number
028-13691
Options
1 call, 1 put
In the 25 largest
80.8%
Prior quarter
$697M at 31 March 2026
Positions opened
17
Positions closed
34

Common questions

What are Sio Capital Management’s 13F holdings worth?

$604 million across 59 positions for the quarter ended 30 June 2026.

What is Sio Capital Management’s largest 13F holding?

ANTERIS TECHNOLOGIES GLOBAL (COM) was the largest position at $54.6 million, or 9.0% of reported 13F value, as of 30 June 2026.

How concentrated is Sio Capital Management’s 13F portfolio?

The ten largest positions accounted for 48.6% of reported value and the twenty-five largest for 80.8%, across 59 positions as of 30 June 2026.

Does Form 13F show everything Sio Capital Management manages?

No. Form 13F covers only long positions in exchange-traded securities over which the manager has investment discretion, valued at quarter end. It excludes cash, most bonds, private funds, and any assets the firm does not have discretion over, so it is neither the firm's total assets nor any individual client's portfolio.

How often does Sio Capital Management file its 13F?

Every quarter. Managers file within 45 days of each quarter's end, so the figures are a snapshot that changes between filings. This page shows the quarter ended 30 June 2026.

Answered from this filing and the prior quarter's.

Back to the Sio Capital Management profile

Sources

  1. Form 13F-HR, accession 0001214659-26-010311, filed 14 August 2026 for the quarter ended 30 June 2026.
  2. Form 13F-HR, accession 0001214659-26-006200, filed 14 May 2026 for the quarter ended 31 March 2026.
  3. All 13F filings by this firm on EDGAR.

Retrieved 14 October 2026. Values are as reported by the filer in whole dollars; percentages and quarter-over-quarter figures are arithmetic on the filed tables.

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This page restates a public SEC filing for informational purposes only. It is not a recommendation of any security or of Sio Capital Management, LLC, and Niva is not affiliated with the firm. Holdings change; the filing reflects one quarter-end date.